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Glossary

Anterograde amnesia

Anterograde amnesia is the inability to form new long-term memories after an injury or illness, while memories from before it stay mostly intact. The person can hold a thought for a few seconds but loses it soon after. The hippocampus is the structure most often involved. It is the mirror image of retrograde amnesia, which erases memories from before the event.

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In more detail

Memory has to move from short-term into long-term storage, a process called consolidation, and the hippocampus and nearby areas in the medial temporal lobe do much of that work. When they are damaged, the first steps still function: the person can follow a conversation and repeat a phone number. But the new content never settles into long-term storage, so it is gone minutes later.

Not every kind of memory is lost. In the famous case of Henry Molaison, known as H.M., surgery in 1953 removed parts of both temporal lobes to treat severe epilepsy. He could no longer form new memories of events and facts, yet he improved at a mirror-drawing task over several days without remembering that he had practiced. Skills and habits (procedural memory) are spared, while memory for events (episodic memory) and facts is hit hardest.

Forget the film version, where a blow to the head makes someone forget who they are. Real amnesia is rarer and narrower than movies show, and this page is for studying the concept, not for diagnosing anything. If you worry about your own memory or someone else's, talk to a doctor.

Anterograde vs retrograde amnesia

FeatureAnterograde amnesiaRetrograde amnesia
What is lostThe ability to form new memories after the eventMemories formed before the event
Direction in timeForward: the future cannot be storedBackward: the past cannot be reached
Older memoriesMostly intactLost, often the most recent ones first
New learning afterwardsSeverely impaired for events and factsUsually possible
Common causesHippocampal damage, head injury, stroke, encephalitis, heavy alcohol use, some sedativesHead injury, stroke, encephalitis, degenerative disease
Classic exampleH.M. after his 1953 surgeryLosing the minutes to years before a head injury
Memory trickAntero: new information does not go inRetro: old information cannot be fetched

Example

A psychology exam asks: a patient chats normally but cannot recall meeting the nurse an hour ago, although he remembers his wedding in 1990. Which type is it? Anterograde amnesia. New events do not become long-term memories, while old ones remain. If the same patient could not remember his wedding but could learn new faces, it would be retrograde.

How StudyPDF does this

Memory disorders are a standard exam topic in psychology and neuroscience. Upload your lecture slides or the textbook chapter, then make a quiz or flashcards on the memory chapter in the New material form. Every card cites the page it came from, and figures from your slides, such as a brain diagram, can sit on the card. Mix both kinds of amnesia in one set so you practice telling them apart.

See also

  • Memory consolidation
  • Long-term memory
  • Episodic memory
  • Retroactive interference
  • Short-term memory

Common questions

What is the difference between anterograde and retrograde amnesia?

Anterograde amnesia blocks new memories formed after the event. Retrograde amnesia erases memories from before it. They can occur together, for example after a severe head injury, and the table above sets them side by side.

Is anterograde amnesia the same as ordinary forgetting?

No. Ordinary forgetting is gradual and happens to everyone, including through interference when new learning disrupts old. Anterograde amnesia is a failure to store new long-term memories because of damage or a drug, not a normal limit of memory.

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